Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ p-Chlorophenylalanine
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CAS: 7424-00-2 Molecular Formula: C9H10ClNO2
| CAS | 7424-00-2 |
|---|---|
| Molecular Formula | C9H10ClNO2 |
Tocris Bioscience™ NSC 636819
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KDM4A/KDM4B inhibitor
| Target | Histone Demethylase Inhibitors |
|---|---|
| CAS | 1618672-71-1 |
| Purity | >98% |
| Chemical Name or Material | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C22H12Cl4N2O4 |
| Formula Weight | 510.15 |
Tocris Bioscience™ HQL 79
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CAS: 162641-16-9 Molecular Formula: C22H27N5O
| CAS | 162641-16-9 |
|---|---|
| Molecular Formula | C22H27N5O |
Tocris Bioscience™ (R)-ZINC 3573
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MRGPRX2 agonist
| Product Type | Agonist |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H21N5 |
| Formula Weight | 307.4 |
Tocris Bioscience™ PF 05190457
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High affinity and selective ghrelin receptor inverse agonist
| CAS | 1334782-79-4 |
|---|---|
| Chemical Name or Material | 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C29H32N6OS |
| Formula Weight | Observed MW: 512.67 |
| Assay Percent Range | >98% |
Tocris Bioscience™ JZP 361, >99%
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Potent and selective reversible MAGL inhibitor
| CAS | 1680193-80-9 |
|---|---|
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Purity | >99% |
| Chemical Name or Material | [4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinyl](1H-1,2,4- |
| Recommended Storage | Store at 4deg;C |
| Formula Weight | 405.88 |
Tocris Bioscience™ PD 161570
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Selective FGFR inhibitor
| Inhibitors | PD 161570 |
|---|---|
| Product Type | PD 161570 |
| Molecular Weight (g/mol) | 532.51 |
| Purity | 0.97 |
Tocris Bioscience™ Lenalidomide 4'-PEG3-amine
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Cereblon ligand with PEG linker and terminal amine for onward chemistry
Tocris Bioscience™ Valdecoxib
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CAS: 181695-72-7 Molecular Formula: C16H14N2O3S
| CAS | 181695-72-7 |
|---|---|
| Molecular Formula | C16H14N2O3S |
Tocris Bioscience™ Tasquinimod
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Tasquinimod is a high affinity negative allosteric modulator of HDAC4 (Kd = 10 to 30 nM).
Tocris Bioscience™ iCRT 14
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CAS: 677331-12-3 Molecular Formula: C21H17N3O2S
| CAS | 677331-12-3 |
|---|---|
| Molecular Formula | C21H17N3O2S |
Tocris Bioscience™ ISO 1
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CAS: 478336-92-4 Molecular Formula: C12H13NO4
| CAS | 478336-92-4 |
|---|---|
| Molecular Formula | C12H13NO4 |
Tocris Bioscience™ cis-VZ 185
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Negative control for VZ 185 (Cat. No. 6936)
Tocris Bioscience™ B02
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RAD51 recombinase inhibitor
| CAS | 1290541-46-6 |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at 4°C |
| Synonym | 3-(Phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone |
| Molecular Formula | C22H17N3O |
| Formula Weight | 339.4 |
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Tocris Bioscience™ NCL 00017509
Tocris Bioscience™ NCL 00017509
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CAS: 1507367-00-1 Molecular Formula: C15H12N6O
| CAS | 1507367-00-1 |
|---|---|
| Molecular Formula | C15H12N6O |